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EBP1, a Novel Host Factor Involved in Primer Binding Site-Dependent Restriction of Moloney Murine Leukemia Virus in Embryonic Cells

Mouse embryonic cells are unable to support the replication of Moloney murine leukemia virus (MLV). The integrated viral DNA is transcriptionally silenced, largely due to binding of host transcriptional repressors to the primer binding site (PBS) of the provirus. We have previously shown that a PBS...

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Bibliographic Details
Main Authors: Wang, Gary Z., Wolf, Daniel, Goff, Stephen P.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911593/
https://ncbi.nlm.nih.gov/pubmed/24227866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02578-13
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