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Enhanced Fusion and Virion Incorporation for HIV-1 Subtype C Envelope Glycoproteins with Compact V1/V2 Domains

In infected people, the HIV-1 envelope glycoprotein (Env) constantly evolves to escape the immune response while retaining the essential elements needed to mediate viral entry into target cells. The extensive genetic variation of Env is particularly striking in the V1/V2 hypervariable domains. In th...

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Detalhes bibliográficos
Main Authors: Cavrois, Marielle, Neidleman, Jason, Santiago, Mario L., Derdeyn, Cynthia A., Hunter, Eric, Greene, Warner C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911571/
https://ncbi.nlm.nih.gov/pubmed/24335304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02308-13
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