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A Novel DDB2-ATM Feedback Loop Regulates Human Cytomegalovirus Replication

Human cytomegalovirus (HCMV) genome replication requires host DNA damage responses (DDRs) and raises the possibility that DNA repair pathways may influence viral replication. We report here that a nucleotide excision repair (NER)-associated-factor is required for efficient HCMV DNA replication. Muta...

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Detalhes bibliográficos
Main Authors: E, Xiaofei, Savidis, George, Chin, Christopher R., Wang, Shixia, Lu, Shan, Brass, Abraham L., Kowalik, Timothy F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911552/
https://ncbi.nlm.nih.gov/pubmed/24335308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03423-13
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