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Genotoxic Stress Prevents Ndd1-Dependent Transcriptional Activation of G(2)/M-Specific Genes in Saccharomyces cerevisiae
Downregulation of specific transcripts is one of the mechanisms utilized by eukaryotic checkpoint systems to prevent cell cycle progression. Here we identified and explored such a mechanism in the yeast Saccharomyces cerevisiae. It involves the Mec1-Rad53 kinase cascade, which attenuates G(2)/M-spec...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Microbiology
2014
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3911480/ https://ncbi.nlm.nih.gov/pubmed/24324010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01090-13 |
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