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Higher Specificity of Nucleic Acid Sequence-Based Amplification Isothermal Technology than of Real-Time PCR for Quantification of HIV-1 RNA on Dried Blood Spots

Dried blood spots (DBS) are widely proposed as a plasma surrogate for monitoring antiretroviral treatment efficacy based on the HIV-1 RNA level (viral load [VL]) in resource-limited settings. Interfering coamplification of cell-associated HIV-1 DNA during reverse transcription (RT)-PCR can be avoide...

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Библиографические подробности
Главные авторы: Mercier-Delarue, Severine, Vray, Muriel, Plantier, Jean Christophe, Maillard, Theodora, Adjout, Zidan, de Olivera, Fabienne, Schnepf, Nathalie, Maylin, Sarah, Simon, Francois, Delaugerre, Constance
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911453/
https://ncbi.nlm.nih.gov/pubmed/24131691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01848-13
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