Enterotoxigenic Escherichia coli Secretes a Highly Conserved Mucin-Degrading Metalloprotease To Effectively Engage Intestinal Epithelial Cells

Enterotoxigenic Escherichia coli (ETEC) is a leading cause of death due to diarrheal illness among young children in developing countries, and there is currently no effective vaccine. Many elements of ETEC pathogenesis are still poorly defined. Here we demonstrate that YghJ, a secreted ETEC antigen...

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Detalhes bibliográficos
Main Authors: Luo, Qingwei, Kumar, Pardeep, Vickers, Tim J., Sheikh, Alaullah, Lewis, Warren G., Rasko, David A., Sistrunk, Jeticia, Fleckenstein, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911403/
https://ncbi.nlm.nih.gov/pubmed/24478067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01106-13
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