Key Role of Toll-Like Receptor 2 in the Inflammatory Response and Major Histocompatibility Complex Class II Downregulation in Brucella abortus-Infected Alveolar Macrophages

Alveolar macrophages (AM) seem to constitute the main cellular target of inhaled brucellae. Here, we show that Brucella abortus invades and replicates in murine AM without inducing cytotoxicity. B. abortus infection induced a statistically significant increase of tumor necrosis factor alpha (TNF-α),...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Ferrero, Mariana C., Hielpos, M. Soledad, Carvalho, Natalia B., Barrionuevo, Paula, Corsetti, Patricia P., Giambartolomei, Guillermo H., Oliveira, Sergio C., Baldi, Pablo C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911380/
https://ncbi.nlm.nih.gov/pubmed/24478078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01237-13
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky