Key Role of Toll-Like Receptor 2 in the Inflammatory Response and Major Histocompatibility Complex Class II Downregulation in Brucella abortus-Infected Alveolar Macrophages

Alveolar macrophages (AM) seem to constitute the main cellular target of inhaled brucellae. Here, we show that Brucella abortus invades and replicates in murine AM without inducing cytotoxicity. B. abortus infection induced a statistically significant increase of tumor necrosis factor alpha (TNF-α),...

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Bibliografski detalji
Glavni autori: Ferrero, Mariana C., Hielpos, M. Soledad, Carvalho, Natalia B., Barrionuevo, Paula, Corsetti, Patricia P., Giambartolomei, Guillermo H., Oliveira, Sergio C., Baldi, Pablo C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911380/
https://ncbi.nlm.nih.gov/pubmed/24478078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01237-13
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