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Targeted Deletion of the Gene Encoding the La Autoantigen (Sjögren's Syndrome Antigen B) in B Cells or the Frontal Brain Causes Extensive Tissue Loss

La antigen (Sjögren's syndrome antigen B) is a phosphoprotein associated with nascent precursor tRNAs and other RNAs, and it is targeted by autoantibodies in patients with Sjögren's syndrome, systemic lupus erythematosus, and neonatal lupus. Increased levels of La are associated with leuke...

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Bibliografske podrobnosti
Main Authors: Gaidamakov, Sergei, Maximova, Olga A., Chon, Hyongi, Blewett, Nathan H., Wang, Hongsheng, Crawford, Amanda K., Day, Amanda, Tulchin, Natalie, Crouch, Robert J., Morse, Herbert C., Blitzer, Robert D., Maraia, Richard J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911279/
https://ncbi.nlm.nih.gov/pubmed/24190965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01010-13
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