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The AlgZR Two-Component System Recalibrates the RsmAYZ Posttranscriptional Regulatory System To Inhibit Expression of the Pseudomonas aeruginosa Type III Secretion System

Pseudomonas aeruginosa causes chronic airway infections in cystic fibrosis (CF) patients. A classic feature of CF airway isolates is the mucoid phenotype. Mucoidy arises through mutation of the mucA anti-sigma factor and subsequent activation of the AlgU regulon. Inactivation of mucA also results in...

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Detalhes bibliográficos
Main Authors: Intile, Peter J., Diaz, Manisha R., Urbanowski, Mark L., Wolfgang, Matthew C., Yahr, Timothy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911257/
https://ncbi.nlm.nih.gov/pubmed/24187093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01199-13
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