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Identification of Legionella pneumophila Effectors Regulated by the LetAS-RsmYZ-CsrA Regulatory Cascade, Many of Which Modulate Vesicular Trafficking

Legionella pneumophila, the causative agent of Legionnaires' disease, is an intracellular human pathogen that utilizes the Icm/Dot type IVB secretion system to translocate a large repertoire of effectors into host cells. To find coregulated effectors, we performed a bioinformatic genomic screen...

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Detalhes bibliográficos
Main Authors: Nevo, Oded, Zusman, Tal, Rasis, Michal, Lifshitz, Ziv, Segal, Gil
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911145/
https://ncbi.nlm.nih.gov/pubmed/24272784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01175-13
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