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Lysosomal enzyme binding to mouse P388D1 macrophage membranes lacking the 215-kDa mannose 6-phosphate receptor: evidence for the existence of a second mannose 6-phosphate receptor.

Mouse P388D1 macrophages target newly synthesized acid hydrolases to lysosomes in spite of their lack of the 215-kDa mannose 6-phosphate (Man-6-P) receptor. We now report that these cells contain a membrane-associated Man-6-P receptor that is distinct from the previously described receptor. The new...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Hoflack, B, Kornfeld, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1985
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391114/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3160044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.13.4428
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