Deregulation of Feedback Inhibition of Phosphoenolpyruvate Carboxylase for Improved Lysine Production in Corynebacterium glutamicum

Allosteric regulation of phosphoenolpyruvate carboxylase (PEPC) controls the metabolic flux distribution of anaplerotic pathways. In this study, the feedback inhibition of Corynebacterium glutamicum PEPC was rationally deregulated, and its effect on metabolic flux redistribution was evaluated. Based...

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Bibliografski detalji
Glavni autori: Chen, Zhen, Bommareddy, Rajesh Reddy, Frank, Doinita, Rappert, Sugima, Zeng, An-Ping
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Biotechnology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911046/
https://ncbi.nlm.nih.gov/pubmed/24334667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03535-13
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