Solanesyl Diphosphate Synthase, an Enzyme of the Ubiquinone Synthetic Pathway, Is Required throughout the Life Cycle of Trypanosoma brucei

Ubiquinone 9 (UQ9), the expected product of the long-chain solanesyl diphosphate synthase of Trypanosoma brucei (TbSPPS), has a central role in reoxidation of reducing equivalents in the mitochondrion of T. brucei. The ablation of TbSPPS gene expression by RNA interference increased the generation o...

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Main Authors: Lai, De-Hua, Poropat, Estefanía, Pravia, Carlos, Landoni, Malena, Couto, Alicia S., Pérez Rojo, Fernando G., Fuchs, Alicia G., Dubin, Marta, Elingold, Igal, Rodríguez, Juan B., Ferella, Marcela, Esteva, Mónica I., Bontempi, Esteban J., Lukeš, Julius
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910978/
https://ncbi.nlm.nih.gov/pubmed/24376001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00271-13
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