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Histatin 5-Spermidine Conjugates Have Enhanced Fungicidal Activity and Efficacy as a Topical Therapeutic for Oral Candidiasis

Oropharyngeal candidiasis (OPC) is caused by the opportunistic fungi Candida albicans and is prevalent in immunocompromised patients, individuals with dry mouth, or patients with prolonged antibiotic therapies that reduce oral commensal bacteria. Human salivary histatins, including histatin 5 (Hst 5...

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Main Authors: Tati, Swetha, Li, Rui, Puri, Sumant, Kumar, Rohitashw, Davidow, Peter, Edgerton, Mira
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910849/
https://ncbi.nlm.nih.gov/pubmed/24247141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01851-13
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