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Histatin 5-Spermidine Conjugates Have Enhanced Fungicidal Activity and Efficacy as a Topical Therapeutic for Oral Candidiasis

Oropharyngeal candidiasis (OPC) is caused by the opportunistic fungi Candida albicans and is prevalent in immunocompromised patients, individuals with dry mouth, or patients with prolonged antibiotic therapies that reduce oral commensal bacteria. Human salivary histatins, including histatin 5 (Hst 5...

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Auteurs principaux: Tati, Swetha, Li, Rui, Puri, Sumant, Kumar, Rohitashw, Davidow, Peter, Edgerton, Mira
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910849/
https://ncbi.nlm.nih.gov/pubmed/24247141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01851-13
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