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Histatin 5-Spermidine Conjugates Have Enhanced Fungicidal Activity and Efficacy as a Topical Therapeutic for Oral Candidiasis
Oropharyngeal candidiasis (OPC) is caused by the opportunistic fungi Candida albicans and is prevalent in immunocompromised patients, individuals with dry mouth, or patients with prolonged antibiotic therapies that reduce oral commensal bacteria. Human salivary histatins, including histatin 5 (Hst 5...
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Auteurs principaux: | , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
American Society for Microbiology
2014
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3910849/ https://ncbi.nlm.nih.gov/pubmed/24247141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01851-13 |
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