Histatin 5-Spermidine Conjugates Have Enhanced Fungicidal Activity and Efficacy as a Topical Therapeutic for Oral Candidiasis

Oropharyngeal candidiasis (OPC) is caused by the opportunistic fungi Candida albicans and is prevalent in immunocompromised patients, individuals with dry mouth, or patients with prolonged antibiotic therapies that reduce oral commensal bacteria. Human salivary histatins, including histatin 5 (Hst 5...

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Autores principales: Tati, Swetha, Li, Rui, Puri, Sumant, Kumar, Rohitashw, Davidow, Peter, Edgerton, Mira
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910849/
https://ncbi.nlm.nih.gov/pubmed/24247141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01851-13
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