Histatin 5-Spermidine Conjugates Have Enhanced Fungicidal Activity and Efficacy as a Topical Therapeutic for Oral Candidiasis

Oropharyngeal candidiasis (OPC) is caused by the opportunistic fungi Candida albicans and is prevalent in immunocompromised patients, individuals with dry mouth, or patients with prolonged antibiotic therapies that reduce oral commensal bacteria. Human salivary histatins, including histatin 5 (Hst 5...

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Autors principals: Tati, Swetha, Li, Rui, Puri, Sumant, Kumar, Rohitashw, Davidow, Peter, Edgerton, Mira
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2014
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910849/
https://ncbi.nlm.nih.gov/pubmed/24247141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01851-13
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