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A Type III Secretion System Inhibitor Targets YopD while Revealing Differential Regulation of Secretion in Calcium-Blind Mutants of Yersinia pestis

Numerous Gram-negative pathogens rely upon type III secretion (T3S) systems to cause disease. Several small-molecule inhibitors of the type III secretion systems have been identified; however, few targets of these inhibitors have been elucidated. Here we report that 2,2′-thiobis-(4-methylphenol) (co...

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Autori principali: Jessen, Danielle L., Bradley, David S., Nilles, Matthew L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910845/
https://ncbi.nlm.nih.gov/pubmed/24247143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01170-13
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