Bactericidal Activity and Mechanism of Action of AZD5847, a Novel Oxazolidinone for Treatment of Tuberculosis

Treatment of tuberculosis (TB) is impaired by the long duration and complexity of therapy and the rising incidence of drug resistance. There is an urgent need for new agents with improved efficacy, safety, and compatibility with combination chemotherapies. Oxazolidinones offer a potential new class...

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Main Authors: Balasubramanian, V., Solapure, S., Iyer, H., Ghosh, A., Sharma, S., Kaur, P., Deepthi, R., Subbulakshmi, V., Ramya, V., Ramachandran, V., Balganesh, M., Wright, L., Melnick, D., Butler, S. L., Sambandamurthy, V. K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2014
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910779/
https://ncbi.nlm.nih.gov/pubmed/24189255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01903-13
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