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Structures of yeast mitochondrial ADP/ATP carriers support a domain-based alternating-access transport mechanism

The mitochondrial ADP/ATP carrier imports ADP from the cytosol and exports ATP from the mitochondrial matrix. The carrier cycles by an unresolved mechanism between the cytoplasmic state, in which the carrier accepts ADP from the cytoplasm, and the matrix state, in which it accepts ATP from the mitoc...

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Autors principals: Ruprecht, Jonathan J., Hellawell, Alex M., Harding, Marilyn, Crichton, Paul G., McCoy, Airlie J., Kunji, Edmund R. S.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910652/
https://ncbi.nlm.nih.gov/pubmed/24474793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320692111
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