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Osteal macrophages support physiologic skeletal remodeling and anabolic actions of parathyroid hormone in bone

Cellular subpopulations in the bone marrow play distinct and unexplored functions in skeletal homeostasis. This study delineated a unique role of osteal macrophages in bone and parathyroid hormone (PTH)-dependent bone anabolism using murine models of targeted myeloid-lineage cell ablation. Depletion...

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Autori principali: Cho, Sun Wook, Soki, Fabiana N., Koh, Amy J., Eber, Matthew R., Entezami, Payam, Park, Serk In, van Rooijen, Nico, McCauley, Laurie K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910564/
https://ncbi.nlm.nih.gov/pubmed/24406853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315153111
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