Pig Lumbar Spine Anatomy and Imaging Guided Lateral Lumbar Puncture: A New Large Animal Model for Intrathecal Drug Delivery

Intrathecal (IT) administration is an important route of drug delivery. Its modeling in a large animal species is a critical step. Although domestic swine is presently a preferred species in preclinical pharmacology, no proven minimally invasive method has been established to deliver agents into the...

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Bibliographic Details
Main Authors: Pleticha, Josef, Maus, Timothy P., Jeng-Singh, Christian, Marsh, Michael P., Al-Saiegh, Fadi, Christner, Jodie A., Lee, Kendall H., Beutler, Andreas S.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910435/
https://ncbi.nlm.nih.gov/pubmed/23518340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2013.03.006
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