The influence of mevinolin on the adrenal cortical response to corticotropin in heterozygous familial hypercholesterolemia.
The biosynthesis of adrenal corticosteroids in humans depends on a continuous supply of cholesterol, which can be derived from both local synthesis and receptor-mediated uptake of low density lipoproteins (LDL) from plasma. Mevinolin, an inhibitor of 3-hydroxy-3-methylglutaryl-CoA reductase [mevalon...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1985
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391039/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2994068/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.18.6291 |
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