MicroRNA-34b inhibits prostate cancer through demethylation, active chromatin modifications and AKT pathways

PURPOSE: MicroRNAs (miRNAs) can act as oncomirs or tumor-suppressor miRs in cancer. This study was undertaken to investigate the status and role of miR-34b in prostate cancer. EXPERIMENTAL DESIGN: Profiling of miR-34b was performed in human prostate cancer (PCa) cell lines and clinical samples by qu...

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Détails bibliographiques
Auteurs principaux: Majid, Shahana, Dar, Altaf A, Saini, Sharanjot, Shahryari, Varahram, Arora, Sumit, Zaman, Mohd Saif, Chang, Inik, Yamamura, Soichiro, Tanaka, Yuichiro, Chiyomaru, Takeshi, Deng, Guoren, Dahiya, Rajvir
Format: Artigo
Langue:Inglês
Publié: 2012
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910324/
https://ncbi.nlm.nih.gov/pubmed/23147995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-2952
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