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Cystic fibrosis decreases the apical membrane chloride permeability of monolayers cultured from cells of tracheal epithelium.

The tracheal mucosa from a 12-year-old girl was digested with collagenase 4 hr after her death from cystic fibrosis. Forty million viable cells were obtained. The cells, plated at 10(6) per cm2 onto four Nuclepore filters coated with human placental collagen, formed confluent monolayers after 1 day....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Widdicombe, J H, Welsh, M J, Finkbeiner, W E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391013/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3862125/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.18.6167
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