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A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice
The progressive bone marrow failure syndrome dyskeratosis congenita (DC) is often caused by mutations in telomerase or the factors involved in telomerase biogenesis and trafficking. However, a subset of DC patients is heterozygous for mutations in the shelterin component TIN2. To determine how the T...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3909789/ https://ncbi.nlm.nih.gov/pubmed/24449270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.233395.113 |
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