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Random sparse sampling strategy using stochastic simulation and estimation for a population pharmacokinetic study

The purpose of this study was to use the stochastic simulation and estimation method to evaluate the effects of sample size and the number of samples per individual on the model development and evaluation. The pharmacokinetic parameters and inter- and intra-individual variation were obtained from a...

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Detalhes bibliográficos
Main Authors: Huang, Xiao-hui, Wang, Kun, Huang, Ji-han, Xu, Ling, Li, Lu-jin, Sheng, Yu-cheng, Zheng, Qing-shan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909756/
https://ncbi.nlm.nih.gov/pubmed/24493975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2013.01.010
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