Integrin-Targeted Molecular Imaging of Experimental Abdominal Aortic Aneurysms by (18)F-FPPRGD(2) Positron Emission Tomography

BACKGROUND: Both inflammation and neoangiogenesis contribute to abdominal aortic aneurysm (AAA) disease. Arg-Gly-Asp (RGD)-based molecular imaging has been shown to detect the integrin α(v)β(3). We studied a clinical dimeric(18)F-labeled RGD positron emission tomography (PET) agent ((18)F-FPPRGD(2))...

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Hlavní autoři: Kitagawa, Toshiro, Kosuge, Hisanori, Chang, Edwin, James, Michelle L., Yamamoto, Tomoaki, Shen, Bin, Chin, Frederick T., Gambhir, Sanjiv S., Dalman, Ronald L., McConnell, Michael V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909706/
https://ncbi.nlm.nih.gov/pubmed/23995363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCIMAGING.113.000234
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