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Insertion of a bacterial gene into the mouse germ line using an infectious retrovirus vector.

Using a Moloney leukemia virus vector containing the bacterial neo gene, we demonstrate that retrovirus vectors can be used to introduce genes into the mouse germ line. Infection of preimplantation embryos with the vector MLV-NEO.1 resulted in integration of neo sequences in approximately equal to 1...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Huszar, D, Balling, R, Kothary, R, Magli, M C, Hozumi, N, Rossant, J, Bernstein, A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390962/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2417225/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8587
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