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Type beta transforming growth factor controls the adipogenic differentiation of 3T3 fibroblasts.

Differentiating mouse 3T3-L1 preadipocytes have been used as a model system to study the ability of type beta transforming growth factor (TGF-beta) to modulate cell development. We find that TGF-beta inhibits potently (ID50 approximately equal to 25 pM) the adipogenic conversion of 3T3-L1 cells. Inh...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ignotz, R A, Massagué, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1985
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC390950/
https://ncbi.nlm.nih.gov/pubmed/3001708
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