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RNA profiling reveals familial aggregation of molecular subtypes in non-BRCA1/2 breast cancer families

BACKGROUND: In more than 70% of families with a strong history of breast and ovarian cancers, pathogenic mutation in BRCA1 or BRCA2 cannot be identified, even though hereditary factors are expected to be involved. It has been proposed that tumors with similar molecular phenotypes also share similar...

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Detalhes bibliográficos
Main Authors: Larsen, Martin J, Thomassen, Mads, Tan, Qihua, Lænkholm, Anne-Vibeke, Bak, Martin, Sørensen, Kristina P, Andersen, Mette Klarskov, Kruse, Torben A, Gerdes, Anne-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909442/
https://ncbi.nlm.nih.gov/pubmed/24479546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-7-9
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