MicroRNA-10a Is Down-Regulated by DNA Methylation and Functions as a Tumor Suppressor in Gastric Cancer Cells

BACKGROUND: MicroRNAs act as posttranscriptional regulators of gene expression in many biological processes. Their deregulations occur commonly in gastric cancer (GC). Although DNA methylation constitutes an important mechanism for microRNA deregulation in cancer, this field largely remains unexplor...

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Autori principali: Jia, Hongyan, Zhang, Zhengyi, Zou, Dongling, Wang, Bin, Yan, Yunmeng, Luo, Min, Dong, Lei, Yin, Haixin, Gong, Bei, Li, Zheng, Wang, Fang, Song, Wei, Liu, Changzheng, Ma, Yanni, Zhang, Junwu, Zhao, Haoliang, Li, Jianxiong, Yu, Jia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909310/
https://ncbi.nlm.nih.gov/pubmed/24498243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088057
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