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p53-Dependent and Cell Specific Epigenetic Regulation of the Polo-like kinases under Oxidative Stress

The polo-like kinase (PLKs) family, consisting of five known members, are key regulators of important cell cycle processes, which include mitotic entry, centrosome duplication, spindle assembly, and cytokinesis. The PLKs have been implicated in a variety of cancers, such as hepatocellular carcinoma...

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Detalhes bibliográficos
Main Authors: Ward, Alejandra, Hudson, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909268/
https://ncbi.nlm.nih.gov/pubmed/24498222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0087918
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