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Multivalent DNA-binding properties of the HMG-1 proteins.

HMG-I proteins are DNA-binding proteins thought to affect the formation and function of transcription complexes. Each protein contains three DNA-binding motifs, known as AT-hooks, that bind in the minor groove of AT tracts in DNA. Multiple AT-hooks within a polypeptide chain should contact multiple...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Maher, J F, Nathans, D
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1996
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39092/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692884/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.13.6716
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