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Release Characteristics of Quetiapine Fumarate Extended Release Tablets Under Biorelevant Stress Test Conditions

The aim of the present work was the investigation of robustness and reliability of drug release from 50 to 400 mg quetiapine extended release HPMC matrix tablets towards mechanical stresses of biorelevant intensity. The tests were performed under standard conditions (USP apparatus II) as well as und...

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Autores principales: Garbacz, Grzegorz, Kandzi, Anna, Koziolek, Mirko, Mazgalski, Jarosław, Weitschies, Werner
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909154/
https://ncbi.nlm.nih.gov/pubmed/24297600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-013-0050-2
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