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Role of the single nucleotide polymorphism rs7903146 of TCF7L2 in inducing nonsense-mediated decay

BACKGROUND: The single nucleotide polymorphism (SNP) rs7903146 (C/T), located in intron 4 of the transcription factor 7-like 2 gene (TCF7L2), has been associated with an increased risk of developing Type 2 Diabetes, although the molecular mechanism remain elusive. The TCF7L2 gene is alternatively sp...

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Detalhes bibliográficos
Main Authors: Nicod, Nathalie, Pradas-Juni, Marta, Gomis, Ramon
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909145/
https://ncbi.nlm.nih.gov/pubmed/24498581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-41
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