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Nonconsensus branch-site sequences in the in vitro splicing of transcripts of mutant rabbit beta-globin genes.

Mutants of the rabbit beta-globin gene lacking the natural site of branch formation in the second intervening sequence have been analyzed for in vitro splicing activity. RNAs transcribed from these mutants were spliced, via lariat formation, at a reduced rate compared to wild-type RNA. The sites of...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Padgett, R A, Konarska, M M, Aebi, M, Hornig, H, Weissmann, C, Sharp, P A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1985
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390913/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3866228/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.24.8349
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