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Maternal Microchimerism: Increased in the Insulin Positive Compartment of Type 1 Diabetes Pancreas but Not in Infiltrating Immune Cells or Replicating Islet Cells

BACKGROUND: Maternal microchimeric cells (MMc) transfer across the placenta during pregnancy. Increased levels of MMc have been observed in several autoimmune diseases including type 1 diabetes but their role is unknown. It has been suggested that MMc are 1) effector cells of the immune response, 2)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ye, Jody, Vives-Pi, Marta, Gillespie, Kathleen M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3909047/
https://ncbi.nlm.nih.gov/pubmed/24498006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086985
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