Block Copolymer/DNA Vaccination Induces a Strong Allergen-Specific Local Response in a Mouse Model of House Dust Mite Asthma

BACKGROUND: Allergic asthma is caused by abnormal immunoreactivity against allergens such as house dust mites among which Dermatophagoides farinae (Der f) is a common species. Currently, immunotherapy is based on allergen administration, which has variable effect from patient to patient and may caus...

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Autores principales: Rolland-Debord, Camille, Lair, David, Roussey-Bihouée, Tiphaine, Hassoun, Dorian, Evrard, Justine, Cheminant, Marie-Aude, Chesné, Julie, Braza, Faouzi, Mahay, Guillaume, Portero, Vincent, Sagan, Christine, Pitard, Bruno, Magnan, Antoine
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908923/
https://ncbi.nlm.nih.gov/pubmed/24497934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085976
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