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Novel Pharmacologic Targeting of Tight Junctions and Focal Adhesions in Prostate Cancer Cells
Cancer cell resistance to anoikis driven by aberrant signaling sustained by the tumor microenvironment confers high invasive potential and therapeutic resistance. We recently generated a novel lead quinazoline-based Doxazosin® derivative, DZ-50, which impairs tumor growth and metastasis via anoikis....
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| Hoofdauteurs: | , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3908921/ https://ncbi.nlm.nih.gov/pubmed/24497940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086238 |
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