Exo70 Isoform Switching upon Epithelial-Mesenchymal Transition Mediates Cancer Cell Invasion

Epithelial-mesenchymal transition (EMT) is an important developmental process hijacked by cancer cells for their dissemination. Here we show that Exo70, a component of the exocyst complex, undergoes isoform switching mediated by ESRP1, a pre-mRNA splicing factor that regulates EMT. Expression of the...

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Main Authors: Lu, Hezhe, Liu, Jianglan, Liu, Shujing, Zeng, Jingwen, Ding, Deqiang, Carstens, Russ P., Cong, Yusheng, Xu, Xiaowei, Guo, Wei
格式: Artigo
語言:Inglês
出版: 2013
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908839/
https://ncbi.nlm.nih.gov/pubmed/24331928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.10.020
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