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Global DNA methylation and one-carbon metabolism gene polymorphisms and the risk of breast cancer in the Sister Study

Global decrease in DNA methylation is a common feature of cancer and is associated with genomic and chromosomal instability. Retrospective case–control studies have reported that cancer patients have lower global methylation levels in blood DNA than do controls. We used prospectively collected sampl...

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Detalhes bibliográficos
Main Authors: DeRoo, Lisa A., Bolick, Sophia C.E., Xu, Zongli, Umbach, David M., Shore, David, Weinberg, Clarice R., Sandler, Dale P., Taylor, Jack A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3908748/
https://ncbi.nlm.nih.gov/pubmed/24130171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt342
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