Загрузка...
Transition-state stabilization in the mechanism of tyrosyl-tRNA synthetase revealed by protein engineering.
The principal catalytic factor in the activation of tyrosine by the tyrosyl-tRNA synthetase is found to be improved binding of ATP in the transition state. The activation reaction involves the attack of the tyrosyl carboxylate on the alpha-phosphate group of ATP to generate a pentacoordinate transit...
Сохранить в:
| Главные авторы: | , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1985
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC390865/ https://ncbi.nlm.nih.gov/pubmed/3865201 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|