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HER4 Selectively Coregulates Estrogen Stimulated Genes Associated with Breast Tumor Cell Proliferation
The EGFR-family member HER4 undergoes regulated intramembrane proteolysis (RIP) to generate an intracellular domain (4ICD) that functions as a transcriptional coactivator. Accordingly, 4ICD coactivates the estrogen receptor (ER) and associates with ER at target gene promoters in breast tumor cells....
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3908545/ https://ncbi.nlm.nih.gov/pubmed/24333426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.11.111 |
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