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Lithium perhydroantamanide complex (2:1): exposure of the peptide backbone in the analog of antamanide with antitoxic impotency.

The synthetic analog of antamanide in which all four phenylalanyl residues are hydrogenated to cyclohexylalanyl (Cha) residues, cyclic(Val-Pro-Pro-Ala-Cha-Cha-Pro-Pro-Cha-Cha), has a complete loss of antitoxic potency despite its ability to form ion complexes in the same manner as antamanide. The co...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autor principal: Karle, I L
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1985
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390807/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3864151/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.21.7155
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