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In Silico Discovery of Aminoacyl-tRNA Synthetase Inhibitors

Aminoacyl-tRNA synthetases (aaRSs) are enzymes that catalyze the transfer of amino acids to their cognate tRNA. They play a pivotal role in protein synthesis and are essential for cell growth and survival. The aaRSs are one of the leading targets for development of antibiotic agents. In this review,...

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Detalhes bibliográficos
Main Authors: Zhao, Yaxue, Meng, Qingqing, Bai, Linquan, Zhou, Huchen
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Diversity Preservation International (MDPI) 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907873/
https://ncbi.nlm.nih.gov/pubmed/24447926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms15011358
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