The replication initiator protein of plasmid pT181 has sequence-specific endonuclease and topoisomerase-like activities.

Initiation of pT181 DNA replication specifically requires the plasmid-encoded RepC protein. Here we demonstrate that highly purified RepC protein has sequence-specific endonuclease and topoisomerase-like activities. A maximum sequence of 127 base pairs containing the pT181 origin of replication is r...

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Bibliographische Detailangaben
Hauptverfasser: Koepsel, R R, Murray, R W, Rosenblum, W D, Khan, S A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1985
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC390784/
https://ncbi.nlm.nih.gov/pubmed/2995991
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