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Biochemical reconstitution of topological DNA binding by the cohesin ring
Cohesion between sister chromatids, mediated by the chromosomal cohesin complex, is a prerequisite for faithful chromosome segregation in mitosis. Cohesin plays vital roles also in DNA repair and transcriptional regulation. The ring-shaped cohesin complex is thought to encircle sister DNA strands, b...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907785/ https://ncbi.nlm.nih.gov/pubmed/24291789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12867 |
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