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Biochemical reconstitution of topological DNA binding by the cohesin ring

Cohesion between sister chromatids, mediated by the chromosomal cohesin complex, is a prerequisite for faithful chromosome segregation in mitosis. Cohesin plays vital roles also in DNA repair and transcriptional regulation. The ring-shaped cohesin complex is thought to encircle sister DNA strands, b...

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Bibliografiske detaljer
Main Authors: Murayama, Yasuto, Uhlmann, Frank
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907785/
https://ncbi.nlm.nih.gov/pubmed/24291789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12867
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