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Effects of a newly developed potent orexin-2 receptor-selective antagonist, compound 1 m, on sleep/wakefulness states in mice
Orexins (also known as hypocretins) play critical roles in the regulation of sleep/wakefulness states by activating two G-protein coupled receptors (GPCRs), orexin 1 (OX(1)R) and orexin 2 receptors (OX(2)R). In order to understand the differential contribution of both receptors in regulating sleep/w...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3907770/ https://ncbi.nlm.nih.gov/pubmed/24550770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2014.00008 |
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