Exosomes from red blood cell units bind to monocytes and induce proinflammatory cytokines, boosting T-cell responses in vitro

Extracellular vesicles (EVs) are small, double membrane vesicles derived from leukocytes, platelets, and cells of other tissues under physiological or pathological conditions. Generation of EVs in stored blood is thought to be associated with adverse effects and potentially immunosuppression in bloo...

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Detalhes bibliográficos
Main Authors: Danesh, Ali, Inglis, Heather C., Jackman, Rachael P., Wu, Shiquan, Deng, Xutao, Muench, Marcus O., Heitman, John W., Norris, Philip J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3907755/
https://ncbi.nlm.nih.gov/pubmed/24335232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-10-530469
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